Download PDF by Haishan Zeng: Diagnostic Endoscopy

By Haishan Zeng

Combining a certified improvement direction on diagnostic endoscopy from SPIE (the overseas society advancing light-based examine) and the authors’ graduate direction on biomedical optics, this paintings is written for researchers in scientific optics and biomedical engineering in addition to graduate clinical optics scholars. It makes use of broad examples/case reviews to familiarize readers with the basics of endoscopic optics, the professionals and cons of white mild endoscopy and fluorescence endoscopy for diagnostic functions, and diverse microscopic endoscopy imaging modalities. It covers simple optics, information of layout and biomedical makes use of, in addition to microscopic endoscopy, and endoscopic spectroscopy.

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This equation describes the color perception quantitatively. 2) then the colors C1 and C2 are perceived to be identical. Hence, two colors that look identical could have different spectral distributions. When α1, α2, and α3 all reach the maximum values, it represents “white” color, while α1 = α2 = α3 = 0 represents black. The properties of different colors can be well described by three perceptual attributes: brightness (or lightness), hue, and saturation. 3 shows a perceptual representation of the color space.

In the early days, measurements are mostly carried out with excised (ex vivo) tissue samples, while recently in vivo method development is intensively studied. A host of investigators have developed various techniques and methods to measure the three transport parameters (μa, μs, g) of various tissues ex vivo (Cheong et al. 1990). In summary, any three of the following four measurements will be sufficient to determine the three parameters: (1) total (or diffuse) transmission for collimated or diffuse irradiance, (2) total (or diffuse) reflection for collimated or diffuse irradiance, (3) unscattered (collimated) transmission for collimated irradiation, and (4) angular distribution of emitted light from an irradiated sample.

Determining the optical properties of turbid media using the adding-doubling method. Appl. Opt. 32: 559–568. , and Palcic, B. 1994. Optical properties of normal and carcinomatous bronchial tissue. Appl. Opt. 33: 7397–7405. , and Campagnola, P. 2008. Optical properties of mutant versus wild-type mouse skin measured by reflectance-mode confocal scanning laser microscopy (rCSLM). J. Biomed. Opt. 13: 041309. , and Tromberg, B. 2001. Non-Invasive Functional Optical Spectroscopy of Human Breast Tissue.

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