PET CT in Clinical Practice by T. B. Lynch PDF

By T. B. Lynch

PET/CT in scientific perform presents guidance for applicable use of PET/CT in lung, lymphoma, esophageal, colorectal, head/neck and cancer, in regards additionally made to tumors of the female and male reproductive process. Concise, suitable and illustrated with many fascinating PET/CT photos, each one bankruptcy incorporates a precis of the proper staging method. the variety of standard PET/CT appearances is printed in bankruptcy nine. The ebook specializes in FDG-PET/CT all through, yet bankruptcy 10 makes connection with the long run program of alternative positron emitters and offers a novices advisor to the physics of PET/CT.
Everyone from clinical scholar to advisor oncologist can be touched by means of this modality and all might want to comprehend its strengths and weaknesses. The e-book is key interpreting for all specialists and scientific scholars in radiology, nuclear medication and oncology.

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Lesions as small as 1 mm to 2 mm can be detected in this way and, although they are too small for accurate characterization by CT, their presence can be identified and monitored with serial imaging. In this patient group, it is suspected that the nodules have a slower rate of growth and are better differentiated, because a lower SUV is associated with longer tumor doubling times and decreased DNA proliferation rates. Therefore a delay in diagnosis may not be as significant within this particular patient group.

DETECTION OF RECURRENT DISEASE The detection of recurrent disease can be hampered by the confounding effects of either radiotherapy or postoperative inflammatory change. If radiotherapy has been given, a post therapy radiation pneumonitis can occur, and although this may have a characteristic appearance on the CT component of the study, it may be difficult to exclude recurrent disease. In these cases it is recommended that a PET/CT scan should not be carried out any less than three months after the therapy to allow any metabolically active macrophage activity within inflammatory lung to resolve preventing a false-positive report.

It is clear that conventional imaging and attempts to obtain histology of small pulmonary nodules is a difficult and often unrewarding exercise. PET/CT has high sensitivity, specificity, and accuracy in the characterization of solitary pulmonary nodules. Many articles have been published with a generally accepted mean sensitivity of about 96%, a lower specificity of 78% and a diagnostic accuracy of over 92%. In general the increased uptake within a pulmonary nodule can be assessed in two ways, either visually, by comparing the intensity of the nodule with the background bloodpool activity or by means of an SUV measurement.

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